• New Columns Maximise HPLC Separation

Environmental Laboratory

New Columns Maximise HPLC Separation

May 12 2014

Waters Corporation (USA) today expanded its family of CORTECS Columns with the introduction of a new line of 2.7 micron silica-based, solid-core particle columns that set a new standard for HPLC column performance. The new set of columns is the newest addition to the Waters CORTECS family of columns. Waters introduced the first – a set of 1.6 micron solid-core particle columns –in 2013. The new columns are being shown at HPLC 2014, the 40th Annual Symposium on High Performance Liquid Phase Separations and Related Techniques.

Designed for analytical scientists who need to maximise performance on their existing LC systems, CORTECS 2.7 micron Columns run at lower pressures while delivering high efficiencies. This gives the scientist the flexibility to use longer column lengths to improve resolution or higher flow rates to speed instrument analysis times and increase throughput.  

Available in C18+, C18, and HILIC chemistries, Waters offers the columns in 48 unique column configurations and is making them immediately available for shipping worldwide.

“With the introduction of CORTECS 2.7 micron Columns, Waters now gives chromatographic laboratories the ability to improve the resolution, speed, and sensitivity of their HPLC separations,” said Michael Yelle, Vice President, Consumables Business Unit, Waters Division. “The advanced solid-core particle design of CORTECS 2.7 micron Columns together with Waters’ 40+ years of column manufacturing expertise put these columns at the head of their class in terms of overall chromatographic performance with the market leading batch-to-batch reproducibility, robustness and quality our customers have come to expect from Waters.”

The new columns complement Waters CORTECS 1.6 micron Columns for UltraPerformance LC (UPLC) introduced in 2013. CORTECS 2.7 micron Columns are fully scalable to CORTECS 1.6 micron Columns, thus allowing separation scientists who currently run HPLC separations the ability to future-proof their laboratories and seamlessly transfer or migrate their separation to UPLC.

CORTECS C18+ columns deliver excellent peak shapes for basic compounds and impart unique selectivity while being a superior low bleed, formic acid-friendly option for LC/MS applications.

CORTECS C18 Columns are general-purpose, high-efficiency, RP columns offering balanced retention of acids, bases, and neutrals at low and mid-range pH. CORTECS C18 Columns provide superb resolution and retention for complex mixtures.

CORTECS HILIC Columns are designed for the retention of extremely polar analytes utilising hydrophilic interaction chromatography (HILIC). Additional benefits include increased mass spectrometry response and compatibility with direct injection of organic extracts from common sample preparation techniques, such as solid-phase extraction (SPE), liquid-liquid extraction (LLE) and protein precipitation (PPT).


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