• Determination and Characterisation of Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS’s) in Environmental Samples

PFAS Analysis

Determination and Characterisation of Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS’s) in Environmental Samples

Perfluoroalkyl and polyfluoroalkyl substances (PFAS’s) are a class of man-made compounds that are frequently detected in biological and environmental samples. PFAS’s are used in a multitude of commercial/industrial processes and products, ranging from fire-fighting foams, insecticide formulations, water-resistant coatings, and floor polishes, to oil-resistant coatings for paper products approved for food contact. As with many anthropogenic compounds, the incidence of cancers resulting from exposure has become a cause for concern.

In this application note we explore the use of the ACQUITY UPLC I-Class System combined with ion mobility as an important tool for the unequivocal identification of PFOS isomers in environmental samples. This technique has been utilised to analyse a series of environmental extracts, including mink and fish muscle, to determine the presence of PFOS. There are some unique advantages to profiling complex matrices using this technique which employs a combination of high resolution mass spectrometry, with high efficiency ion mobility-based measurements and separations. Ion mobility spectrometry (IMS) is a rapid, orthogonal, gas phase separation technique which allows another dimension of separation to be obtained within an LC timeframe. Compounds can be differentiated based on size, shape, and charge. In addition, both precursor ion and fragment ion information can be acquired in a single injection for all components analysed.


Digital Edition

AET 28.4 Oct/Nov 2024

November 2024

Gas Detection - Go from lagging to leading: why investment in gas detection makes sense Air Monitoring - Swirl and vortex meters will aid green hydrogen production - Beyond the Stack: Emi...

View all digital editions

Events

World Future Energy Summit

Jan 14 2025 Abu Dhabi, UAE

Clean Fuels Conference

Jan 20 2025 San Diego, CA, USA

Carrefour des Gestions Locales de L'eau

Jan 22 2025 Rennes, France

Safety, Health & Wellbeing LIVE

Jan 22 2025 Manchester, UK

SLAS 2025

Jan 25 2025 San Diego, CA, USA

View all events