Chromatography

The use of LC-MS/MS and GC-MS/MS in the sports, healthcare and pharmaceuticals sectors

Author: Dr Philip Grace and Dr Michael van der Merwe on behalf of HFL Ltd

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Established more than 40 years ago, HFL is the only laboratory in the world engaged in both contract research and drug surveillance screening to protect the integrity of human and animal sports. This unique background in high-integrity analysis adds an extra dimension to HFL?s services supporting pharmaceutical and biopharmaceutical development. Operating from state-of-the-art facilities near Cambridge, UK, HFL provides laboratory services supporting four major sectors; pharmaceutical, sports, healthcare and government. With a unique blend of core expertise and capabilities in proteomics, immunochemistry, chromatography and mass spectrometry, HFL has particular strengths in high-sensitivity, quantitative analysis of small chemical entities and large biological molecules in biological matrices. This paper describes four case examples applying LC-MS/MS, GC/MS/MS and uHPLC technologies to support our activities in these sectors.

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